Analytical Information

The CFSRE and the SOFT NPS Committee have established the below recommendations for NPS scope based on information from extensive collaborations, partnerships, and initiatives which yield national perspectives. For more information about our scope recommendations, email the NPS Discovery Program Manager or the SOFT NPS Committee Chairs, Dani Mata and Kayla Ellefsen  

NPS Scope Recommendations

The SOFT NPS Committee also publishes analytical profiles of emerging novel psychoactive substances and new drug articles periodically throughout the year in ToxTalk. Below is a list of some of the most recent publications:

• "It's Alive!": Protonitazene, the Latest ‘Frankenstein Opioid’
• The Repurposing of Tianeptine
• To Drop or Not to Drop: An NPS Question
• The Increasing Scope of Designer Benzodiazepines: Details on 4’-Chloro Deschloroalprazolam and Clonazolam
• New Drugs on the Block: Spring 2022 Line-Up 

NPS Libraries and Drug Identification Tools: 

• Cayman Spectral Library: http://www.caymanchem.com/forensics/publications/csl [caymanchem.com]  
• Cayman GC-MS Drug Identification Tool: http://www.caymanchem.com/forensics/search/drugId [caymanchem.com]
• NPS Discovery GC-MS Library (Readable in Agilent MSD ChemStation): https://www.cfsre.org/nps-discovery/monographs [cfsre.org]  
• NPS Discovery LC-QTOF Library (Readable with SCIEX LibraryView): https://www.cfsre.org/nps-discovery/monographs [cfsre.org]
• HighResNPS: https://highresnps.forensic.ku.dk/ [highresnps.forensic.ku.dk] (request login with full name, laboratory and email at: [email protected])”

Drug Monographs

Drug Monographs

Here you can find short communications for emerging NPS and drug monographs containing detailed information about pharmacological drug class, metabolism, blood concentrations, effects / toxicity, and analysis. Click on a drug name below to access the document:

• 4F-MDMB-BINACA
• Flualprazolam 
• Isotonitazene 
• Mitragynine/7-Hydroxymitragynine   
• N-Ethylpentylone 

In addition, SWGDRUG has graciously allowed this committee to link to their website.  Zolazepam.

Additionally, the CFSRE and NPS Discovery publishes new drug monographs on their website: NPS Discovery Monographs

 NPS Literature 

Coming Soon! 

 Useful Links

Analytical

• SWGDRUG
• Southern Association for Scientists
• Midwest Association for Toxicology and Therapeutic Drug Monitoring
• TIAFT NPS Committee
• Compound Search
• NPS Discovery
• NPS Scope Recommendations

Legislation

• DEA: https://www.dea.gov/
• FDA: https://www.fda.gov/

 Analytical Standards

• Cerilliant
• Lipomed
• Toronto Research Chemicals Inc.
• Cayman Chemical
• LGC Standards

 Drug User Forums

• Drugs Forum
• EROWID

 Trend Reports

• NPS Discovery Trend Reports
• UNODC NPS Early Warning Advisory
• DEA Emerging Threat Reports
• NFLIS Publications
• NFLIS DEA Synth-Opioids Real-time Communication Network  
• National Early Drug Warning System (subscribe to weekly briefings)